Welcome to
Sysmex Flow Cytometry France!

For ordering please make sure you are in your local shop.
If you are from France then please continue.
Otherwise please go to your country.

Go to my country Continue

CyFlow™ CD62L Alexa Fluor™ 700

CyFlow™ CD62L Alexa Fluor™ 700
Antigen: CD62L
Alternative Name: L-Selectin
Clone: DREG56
Application: Flow cytometry
Format/Fluorochrome: Alexa Fluor™ 700
Laser: Red
Target Species: Human
Field of Interest: Immunophenotyping
Species of Origin: Mouse
Regulatory Status: RUO
Clonality: monoclonal
Emission Maximum: 723 nm
Excitation Maximum: 702 nm
Isotype: IgG1
Order number: AU807163

For Research Use Only
Not for use in diagnostic or therapeutic procedures.

Quantity 100 tests Volume 0.4 ml Immunogen PMA-activated human peripheral blood... more
CyFlow™ CD62L Alexa Fluor™ 700
Quantity100 tests
Volume0.4 ml
ImmunogenPMA-activated human peripheral blood leukocytes
SpecifityThe mouse monoclonal antibody DREG56 recognizes CD62L antigen, a 65-76 kDa cell surface protein, expressed by neutrophils, monocytes, and subsets of T, B, and NK cells, that interacts with specific carbohydrates exposed on activated endothelial cells.
Background InformationCD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1). The level of CD62L expression can be used to help distinguish naive T cells from effector/memory T cells.
UsageThe reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.

Article successfully added.