Welcome to
Sysmex Flow Cytometry France!

For ordering please make sure you are in your local shop.
If you are from France then please continue.
Otherwise please go to your country.

Go to my country Continue

CyFlow™ CD46 Azide Free

CyFlow™ CD46 Azide Free
Antigen: CD46
Alternative Name: MCP
Clone: MEM-258
Application: Flow cytometry, Immunoprecipitation, Western blot
Format/Fluorochrome: Azide Free
Target Species: Cow, Human
Field of Interest: Immunophenotyping
Species of Origin: Mouse
Regulatory Status: RUO
Clonality: monoclonal
Isotype: IgG1
Order number: BZ758453

For Research Use Only
Not for use in diagnostic or therapeutic procedures.

Concentration 1 mg/ml Quantity 0.1 mg Volume 0.1 ml Immunogen HPB-ALL human T... more
CyFlow™ CD46 Azide Free
Concentration1 mg/ml
Quantity0.1 mg
Volume0.1 ml
ImmunogenHPB-ALL human T cell line
SpecifityThe mouse monoclonal antibody MEM-258 recognizes an epitope on SCR4 (the membrane-proximal SCR) domain of CD46 antigen, a 56-66 kDa dimeric transmembrane protein expressed on T and B lymphocytes, platelets, monocytes, granulocytes, endothelial cells, epithelial cells and fibroblast; it is negative on erythrocytes.
Background InformationCD46 (MCP; membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.
Storage BufferThe reagent is provided in azide-free phosphate buffered saline (PBS) solution, pH ≈7.4; 0.2 µm filter sterilized.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.

Article successfully added.