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CyFlow™ CD21 Purified

CyFlow™ CD21 Purified
Application: Flow cytometry, Immunohistochemistry (frozen sections)
Target Species: Cow, Dog, Human, Pig
Clone: LT21
Alternative Name: C3dR, CR2, EBV-R
Antigen: CD21
Clonality: monoclonal
Isotype: IgG1
Format/Fluorochrome: Purified
Field of Interest: Immunophenotyping
Source Species: Mouse
Regulatory Status: RUO
Order number: BJ686541
HLDA Workshop HLDA VI—WS Code B CD21.1 Concentration Unit mg/mL Concentration 1... more
Product information "CyFlow™ CD21 Purified"
HLDA WorkshopHLDA VI—WS Code B CD21.1
Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenIM9 human B-lymphoblastoid cell line
Background InformationCD21 (CR2; complement receptor 2) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to folicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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* All prices are quoted net of the statutory value-added tax and shipping costs and possibly delivery charges, if not otherwise described

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