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CyFlow™ CD7 PE-Cy5

CyFlow™ CD7 PE-Cy5
Application: Flow cytometry
Clonality: monoclonal
Target Species: Human
Regulatory Status: RUO
Laser: Blue, Green, Yellow
Source Species: Mouse
Field of Interest: Immunophenotyping
Excitation Maximum: 496 nm, 565 nm
Isotype: IgG1
Format/Fluorochrome: PE-Cy5
Emission Maximum: 670 nm
Antigen: CD7
Alternative Name: gp40
Clone: MEM-186
Order number: CE144338
CD7 (gp40) is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes,... more
Product information "CyFlow™ CD7 PE-Cy5"
CD7 (gp40) is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion. A ligand of CD7, epithelial cell secreted protein K12, is produced in thymus to regulate thymocyte signaling and cytokine release. In lung microvascular endothelial cells CD7 serves as an IgM Fc receptor. Expression of CD7 is an important marker used in leukemia diagnostics.
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* All prices are quoted net of the statutory value-added tax and shipping costs and possibly delivery charges, if not otherwise described

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